Pharmaceutical Importance and Synthetic Strategies for Imidazolidine-2-thione and Imidazole-2-thione Derivatives
نویسندگان
چکیده
منابع مشابه
Pentacarbonyl(imidazolidine-2-thione-κS)tungsten(0)
In the title complex, [W(C(3)H(6)N(2)S)(CO)(5)], the W atom displays an octa-hedral coordination with five CO mol-ecules and an imidazolidine-2-thione mol-ecule. The W(CO)(5) unit is coordinated by the cyclic thione ligand through a W-S dative bond. The W-S and C-S bond lengths are 2.599 (2) and 1.711 (9) Å, respectively. This last distance is significantly longer than that of free cyclic thio-...
متن کامل1,3-Bis(1-phenylethyl)imidazolidine-2-thione
The complete molecule of the title compound, C(19)H(22)N(2)S, is generated by crystallographic twofold symmetry with the C=S group lying on the rotation axis. The imidazolidine ring adopts a flattened twist conformation. The dihedral angle between the asymmetric part of the imidazolidine-2-thione fragment and the benzene ring is 89.49 (17)°.
متن کامل1,3-Bis(1-cyclohexylethyl)imidazolidine-2-thione
The complete mol-ecule of the title compound, C(19)H(34)N(2)S, is generated by crystallographic twofold symmetry, with the C=S group lying on the rotation axis. A short C-H⋯S contact occurs in the mol-ecule. The five-membered ring is twisted and the cyclo-hexyl ring adopts a chair conformation. The dihedral angle between the mean plane of the five-membered ring and the basal plane of the cyclo-...
متن کامل4-Phenyl-1H-imidazole-2(3H)-thione
In the asymmetric unit of the title compound, C(9)H(8)N(2)S, there are four symmetry-independent mol-ecules (Z' = 4). The geometrical features of these mol-ecules are quite similar: in the normal probability plots the R(2) correlation factors for bond lengths and angles are generally around 0.95. The twist angles between the imidazole and phenyl rings (which are planar within 3σ) range from 9.0...
متن کاملtrans-4,5-Dihydroxy-1,3-bis(4-methoxyphenyl)imidazolidine-2-thione
In the title compound, C(17)H(18)N(2)O(4)S, where one of the N-4-methoxy-phenyl fragments is disordered over two sets of sites, the five-membered ring exhibits a nearly half-chair conformation and the two hydroxyl groups lie on opposite sides of the five-membered ring. In the crystal, the mol-ecules are linked into sheets parallel to (100) via O-H⋯O and O-H⋯S hydrogen bonds.
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ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2011
ISSN: 1028-8880
DOI: 10.3923/pjbs.2011.1076.1089